# Pharmaceutical Sciences

## Thursday, February 5, 2015

## Monday, February 18, 2013

### Pharmacokinetics

One Compartmental Modeling - IV Bolus

Linear Elimination

Laplace Transformation

Two Compartmental Model IV Bolus

Two Compartmental Model - Slopes and Intercepts

Two Compartmental Model - PK Parameters Concepts

Two Compartmental Model - Slopes and Intercepts Calculations

Two Compartmental Model - PK Parameters Calculations

Old Videos

Calculations 1

Calculations 2

Calculations 3

Bioavailability

Bioavailability - Method of Residuals

Bioavailability Calculations

Linear Elimination

Laplace Transformation

Two Compartmental Model IV Bolus

Two Compartmental Model - Slopes and Intercepts

Two Compartmental Model - PK Parameters Concepts

Two Compartmental Model - Slopes and Intercepts Calculations

Two Compartmental Model - PK Parameters Calculations

Old Videos

Calculations 1

Calculations 2

Calculations 3

Bioavailability

Bioavailability - Method of Residuals

Bioavailability Calculations

## Friday, January 18, 2013

### Renal Module: Pharmacokinetics

Dosing During Renal Impairment

Glomerular Filtration and Secretion Calculations

Cockroft and Gault Equation Weight Considerations

Dosing in Renal Impairment Calculations

Dosing in Renal Impairment: Renal Fudge Factor Calculations 1

Dosing in Renal Impairment: Renal Fudge Factor Calculations 2

Dosing During Dialysis

Dialysis - Gwilt and Perrier Equation Calculations

Dialysis - Intradialytic Calculations

Dialysis - Dose Replacement Calculations

Dialysis - Therapeutic Range Calculations

Ionization of Drug in Blood and Urine

Percent Ionized Calculations

Glomerular Filtration and Secretion Calculations

Cockroft and Gault Equation Weight Considerations

Dosing in Renal Impairment Calculations

Dosing in Renal Impairment: Renal Fudge Factor Calculations 1

Dosing in Renal Impairment: Renal Fudge Factor Calculations 2

Dosing During Dialysis

Dialysis - Gwilt and Perrier Equation Calculations

Dialysis - Intradialytic Calculations

Dialysis - Dose Replacement Calculations

Dialysis - Therapeutic Range Calculations

Ionization of Drug in Blood and Urine

Percent Ionized Calculations

## Thursday, January 17, 2013

### Pharmacodynamics

Basic Pharmacological Response

Drug Receptor Theory Introduction

Emax Equation from Drug Receptor Theory

Emax Equation Linearization

Emax Calculations

Properties of Hill function

E = S*C

E = S*C+ E0

E = Emax*C/EC50+C

Drug Dosing - Non Linear Pharmacokinetics : Part 1

Drug Dosing - Non Linear Pharmacokinetics : Part 2

Sigmoid Emax model - Hill factor

Solving n or sigmoidicity

Intercept of sigmoidicity

Basic Pharmacological Response (Old Files)

Scatchard Plot Linearization

Drug Receptor Theory Introduction

Emax Equation from Drug Receptor Theory

Emax Equation Linearization

Emax Calculations

Properties of Hill function

E = S*C

E = S*C+ E0

E = Emax*C/EC50+C

Drug Dosing - Non Linear Pharmacokinetics : Part 1

Drug Dosing - Non Linear Pharmacokinetics : Part 2

Sigmoid Emax model - Hill factor

Solving n or sigmoidicity

Intercept of sigmoidicity

Basic Pharmacological Response (Old Files)

Scatchard Plot Linearization

## Tuesday, October 30, 2012

### Pharmaceutics

Isotonicity Calculations

L Method

E Method

Cryoscopic Methods

Interfacial Phenomena

Surface Tension

Spreading Coefficient

HLB

Suspensions

Stoke's Law

Stoke's Law Assumptions

Sedimentation Rate Calculations

L Method

E Method

Cryoscopic Methods

Interfacial Phenomena

Surface Tension

Spreading Coefficient

HLB

Suspensions

Stoke's Law

Stoke's Law Assumptions

Sedimentation Rate Calculations

## Sunday, September 30, 2012

### Pharmaceutical Compounding

Week 1 (By TA's Jacob Vogel & Louis Dellapina)

Log Reports and Printing

Torsion Balance

Weigh Boat

Adjusting Electronic Weigh Balance

Week 2 Equipment (By TA's Jacob Vogel & Louis Dellapina)

Capsule Machine

Ointment Mill

Unguator

Week 2 Drills

Wetting Agents

Powder Trituration + Geometric Addition

Measuring Techniques

Ointment Levigation

Geometric Dilution

Week 3 Drills

Suppositories Double Casting Technique Lecture

Suppositories Double Casting Preparation

Carbomer Gel

Week 4 Drills

Emulsions

Poloxamer Gel

Capsules Calculations

Capsules Filling

Week 5 Drills

Suppositories Double Casting Preparation

Lip Balm/Soft Sticks

Troches/Lozenges

Lollipops/Hard Lozenges

Week 6 Drills

Rx Labels

Log Reports and Printing

Torsion Balance

Weigh Boat

Adjusting Electronic Weigh Balance

Week 2 Equipment (By TA's Jacob Vogel & Louis Dellapina)

Capsule Machine

Ointment Mill

Unguator

Week 2 Drills

Wetting Agents

Powder Trituration + Geometric Addition

Measuring Techniques

Ointment Levigation

Geometric Dilution

Week 3 Drills

Suppositories Double Casting Technique Lecture

Suppositories Double Casting Preparation

Carbomer Gel

Week 4 Drills

Emulsions

Poloxamer Gel

Capsules Calculations

Capsules Filling

Week 5 Drills

Suppositories Double Casting Preparation

Lip Balm/Soft Sticks

Troches/Lozenges

Lollipops/Hard Lozenges

Week 6 Drills

Rx Labels

## Saturday, September 1, 2012

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